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Possible monitoring points include injection site irritation, flushing, dizziness, headache, nausea, or temporary sleep and appetite changes

MPTP and 3-NP manipulations were carried out in a restricted room in the Cornell animal facility specified for neurotoxin manipulation

It plays integral roles in: Immune regulation Cancer suppression (anti-proliferative and pro-apoptotic signaling) Mitochondrial function and redox balance Hormonal feedback loops, including cortisol and estrogen/testosterone rhythms Aging diminishes melatonin output by up to 75%, leading to weaker circadian cues and downstream systemic dysfunction

Inject on Thursday instead of the following Monday